Therapeutic combinations comprising a selective estrogen...

Details Therapeutic combinations comprising a selective estrogen... Therapeutic combinations comprising a selective estrogen...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/557 (2006.01)

Patent

CA 2274381

This invention is directed to pharmaceutical combination compositions and methods comprising (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)- 5,6,7,8- tetrahydronaphthalene-2-of or a pharmaceutically acceptable salt thereof and PGE2 or a pharmaceutically acceptable salt thereof, methods of using such compositions and kits containing such compositions. The compositions are useful for treating musculoskeletal frailty, including osteoporosis, osteoporotic fracture, low bone mass and frailty.

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