Antibody compositions and methods

Details Antibody compositions and methods Antibody compositions and methods

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01)

Patent

CA 2539999

Provided are concentrated preparations comprising single immunoglobulin variable domain polypeptides that bind target antigen with high affinity and are soluble at high concentration, without aggregation or precipitation, providing, for example, for increased storage stability and the ability to administer higher therapeutic doses.

L'invention concerne des préparations concentrées qui renferment des polypeptides à domaine variable d'immunoglobuline unique se liant à un antigène cible avec une affinité élevée et qui sont solubles à haute concentration, sans agrégation ni précipitation, assurant par exemple une stabilité de stockage accrue et un potentiel d'administration sous des doses thérapeutiques supérieures.

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