Compositions and methods for preventing or reducing plaque...

Details Compositions and methods for preventing or reducing plaque... Compositions and methods for preventing or reducing plaque...

A - Human Necessities

61

K

A61K 8/25 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2549787

Methods and compositions for the prevention and/or reduction of plaque, plaque build-up and/or gingivitis are provided. Bioactive glass compositions are provided which prevent or reduce plaque, plaque build-up and/or gingivitis through the use of low levels of small bioactive glass particles in amounts from about 0.25 to about 10% by weight in non-aqueous formulations. The resulting non-aqueous compositions are effective in dentifrice products and are stable and pass ISO (International Organization for Standardization) standards. Moreover, these bioactive glass containing non-aqueous compositions have unexpectedly high levels of antimicrobial activity against oral pathogens.

L'invention concerne des procédés et des compositions de prévention et/ou de réduction de la plaque dentaire ainsi que de sa formation et/ou de la gingivite. L'invention concerne des compositions de verre bioactif qui empêchent et réduisent la plaque dentaire, sa formation et/ou la gingivite grâce à l'utilisation de faibles niveaux de petites particules de verre bioactif en doses comprises entre environ 0,25 et environ 10 % en poids dans des formulations non aqueuses. Les compositions non aqueuses ainsi obtenues sont efficaces dans des produits dentifrices, et sont stables et conformes aux normes ISO (Organisation internationale de normalisation). De plus, ces compositions non aqueuses contenant du verre bioactif possèdent des niveaux d'activité antimicrobienne contre les agents pathogènes oraux exceptionnellement élevés.

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