C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/14 (2006.01) A61K 31/404 (2006.01) A61K 45/06 (2006.01) C07D 209/10 (2006.01) C07D 209/18 (2006.01)
Patent
CA 2498493
The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-indole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents. This invention further relates to small molecules which suppress cytokines and leukocytes.
La présente invention se rapporte à des inhibiteurs de petites molécules de l'IgE en réponse aux allergènes que l'on utilise dans le traitement d'allergies et/ou de l'asthme ou d'autres maladies dans lesquelles IgE s'avère pathogène. L'invention se rapporte également à des molécules de phényle-indole qui sont des inhibiteurs de la prolifération cellulaire et servent, de ce fait, d'agents anticancéreux. L'invention concerne en outre de petites molécules supprimant les cytokines et les leucocytes.
Ramnauth Jailall
Richards Mark L.
Sircar Jagadish C.
Avanir Pharmaceuticals
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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