Propofol formulation containing tris

Details Propofol formulation containing tris Propofol formulation containing tris

A - Human Necessities

61

K

A61K 47/18 (2006.01) A61K 9/107 (2006.01) A61K 31/05 (2006.01) A61K 31/13 (2006.01)

Patent

CA 2367093

Sterile pharmaceutical compositions for parenteral administration containing propofol in an oil-in-water emulsion additionally containing an amount of the preservative tromethamine sufficient to prevent significant growth of microorganisms for at least 24 hours after extrinsic contamination.

L'invention concerne des compositions pharmaceutiques stériles destinées à être administrées par voie parentérale et contenant du propofol dans une émulsion de type aqueux, elle-même contenant une quantité du conservateur trométhamine suffisante pour prévenir une croissance sensible de micro-organismes au moins pendant les 24 heures suivant une contamination extrinsèque.

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