C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/06 (2006.01) A61K 31/403 (2006.01) A61K 31/535 (2006.01) A61K 31/5383 (2006.01) A61P 25/00 (2006.01) C07D 209/00 (2006.01) C07D 265/00 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2460126
The present invention provides compounds of Formula (I) wherein: R1, R2, R3, R4, R5, R6, R7, R8, n, m, and X have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of Formula (I). The compounds are 5-HT ligands and are useful for treating diseases wherein modulation of 5-HT activity is desired.
L'invention concerne des composés de formule (I): dans laquelle R1, R2, R3, R4, R5, R6, R7, R8, n, m, et X ont les valeurs indiquées dans la description, ainsi que des compositions pharmaceutiques à base desdits composés. L'invention concerne également des méthodes thérapeutiques ainsi que des procédés et des produits intermédiaires utiles à des fins de préparation des composés de formule (I). Lesdits composés sont des ligands du récepteur 5-HT et sont utiles à des fins de traitement de maladies pour lesquelles la modulation de l'activité de récepteurs 5-HT est désirée.
Macrae & Co.
Pharmacia & Upjohn Company
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