Preparation and administration of hybrid cell vaccines for...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 35/12 (2006.01) A61K 38/19 (2006.01) C12N 15/02 (2006.01) C12N 15/07 (2006.01) A01N 65/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2508209

The present invention relates to methods for preventing cancer and for treating and preventing development and progression of pre-cancerous lesions by administering a therapeutically effective dose of fusion cells formed by fusion of dendritic cells and precancerous non-dendritic cells, either alone or in combination with a cytokine or other molecule which stimulates or induces a cytotoxic T cell response and/or a humoral immune response.

La présente invention concerne des méthodes de prévention du cancer et de traitement ou de prévention du développement et de la progression de lésions précancéreuses, consistant à administrer une dose efficace au plan thérapeutique de cellules obtenues par la fusion de cellules dendritiques et de cellules non dendritiques précancéreuses, soit seules, soit en combinaison avec une citokyne ou autre molécule qui stimule ou induit une réponse des lympocytes t cytotoxiques et/ou une réponse immunitaire humorale.

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