C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 15/00 (2006.01) A61K 31/282 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2751068
The invention provides polypeptide-platinum conjugates comprising an anticancer platinum complex conjugated to polypeptides that bind relatively specifically to cancer cells, so as to direct the conjugates to cancer cells resulting in increased anticancer efficacy and decreased side-effects as compared to cisplatin and other conventional anti-cancer platinum complexes.
L'invention concerne des conjugués polypeptide-platine comprenant un complexe de platine anticancéreux conjugué à des polypeptides qui se lient relativement spécifiquement à des cellules cancéreuses, de façon à diriger les conjugués vers les cellules cancéreuses, ce qui permet d'augmenter l'efficacité anticancéreuse et de réduire les effets secondaires par rapport au cisplatine et à d'autres complexes de platine anticancéreux classiques.
Borden Ladner Gervais Llp
Igf Oncology Llc
LandOfFree
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