Network of buoyant particles for biomolecule purification

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2613094

A network of buoyant particles for clearing lysates of biological material, the network including two or more buoyant particles covalently linked together, wherein the network ranges in size from approximately 30 microns to approximately one centimeter along the network's longest dimension. The buoyant particles may have a silica surface. The network may have a density less than about 1.2 g/cm3. Methods of making the network of buoyant particles and methods of isolating target biological material using buoyant particles or a network of buoyant particles are also described.

La présente invention concerne un réseau de particules flottantes destiné à éclaircir des lysats de matériau biologique, ce réseau comprenant au moins deux particules flottantes liées de manière covalente entre elles, ce réseau étant compris entre approximativement 30 microns et approximativement 1 cm dans sa plus grande dimension. Ces particules flottantes peuvent avoir une surface de silice. Ce réseau peut posséder une densité inférieure à environ 1,2 g/cm3. Cette invention concerne aussi des procédés de fabrication de ce réseau de particules et des procédés permettant d'isoler un matériau biologique cible au moyen de ces particules flottantes ou d'un réseau de particules flottantes.

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