A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/02 (2006.01) C07K 14/315 (2006.01) C07K 14/715 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2149703
Mucosal administration, particularly intranasally, of killed whole pneumococci, lysate of pneumococci and isolated and purified PspA, as well as immunogenic fragments thereof, particularly when administered with cholera toxin B subunit, provides protection in animals against pneumococcal colonization and systemic infection. The ability to elicit protection against pneumococcal colonization in a host prevents carriage among immunized individuals, which can lead to elimination of disease from the population as a whole.
Briles David E.
Wu Hong-Yin
Smart & Biggar
Uab Research Foundation
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