G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2372645
The present invention pertains to the field of medicine and essentially relates to methods for screening drug preparations and mainly for selecting a preparation and optimally dosing the same in order to treat a physical patient. The method involves selecting a drug preparation according to the results from the culture of a patient's whole blood in which heparin has been added and in the presence of aqueous solutions of comparative preparations. The method further involves analysing the ratio of the -SH and -SS- groups in the cellular fraction of the patient's blood after cultivation, and the preparation selected is the one presenting the most adequate ratio. This method reduces the screening duration down to a few hours and can be used for treating viral, cancerous, auto-immune and other conditions.
Cette invention se rapporte au domaine de la médecine, et concerne plus précisément des procédés de criblage de préparations médicamenteuses et, notamment, de sélection d'une préparation et du dosage optimal de celle-ci afin de traiter un patient physique. On sélectionne la préparation médicamenteuse en fonction des résultats de la culture du sang entier d'un patient auquel on a ajouté de l'héparine, ceci en présence de solutions aqueuses de préparations de comparaison. On analyse ensuite le rapport des groupes -SH et -SS- dans la fraction cellulaire du sang du patient après culture, et la préparation retenue est celle qui présente le rapport le plus intéressant. Ce procédé permet de réduire le temps de criblage à quelques heures, et peut être utilisé afin de traiter des affections virales, cancéreuses, auto-immunes ou autres.
Mccarthy Tetrault Llp
Volchek Igor Vladimirovich
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