Genes which influence pichia proteolytic activity, and uses...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/57 (2006.01) C07K 14/65 (2006.01) C12N 1/19 (2006.01) C12N 9/48 (2006.01) C12N 9/60 (2006.01) C12N 9/88 (2006.01) C12N 15/11 (2006.01) C12N 15/53 (2006.01) C12N 15/60 (2006.01) C12N 15/81 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2105064

2105064 9217595 PCTABS00016 The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia that are deficient in proteolytic activity and useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefor.

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