A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/52 (2006.01) A61K 9/70 (2006.01) A61K 47/30 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01)
Patent
CA 2187353
Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a controlled release implant. Methods of forming a controlled release implant and employing the liquid formulations in the treatment of a subject are also provided.
Compositions liquides biocompatibles améliorées administrables pour dispositifs de libération prolongée d'agents actifs. Ces compositions comportent des formulations liquides d'un polymère ou d'un prépolymère biocompatible associé à un constituant à libération contrôlée contenant un agent actif. Lesdites compositions peuvent s'injecter dans le corps du patient sous forme d'un liquide qui se solidifie ou se durcit in situ en formant un implant à libération contrôlée ou un pansement pelliculaire, ou s'employer ex situ sous forme d'implant à libération contrôlée. L'invention porte également sur les procédés de formation desdits implants et d'emploi desdites formulations à des fins curatives.
Brouwer Gerbrand
Dunn Richard L.
Krinick Nancy L.
Radomsky Michael L.
Tipton Arthur J.
Atrix Laboratories Inc.
Goudreau Gage Dubuc
Qlt Usa Inc.
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