Injectable bone-replacement mixture

Details Injectable bone-replacement mixture Injectable bone-replacement mixture

A - Human Necessities

61

L

A61L 24/00 (2006.01) A61L 27/16 (2006.01) A61L 27/50 (2006.01) A61L 27/56 (2006.01)

Patent

CA 2516113

An injectable mixture for substituting bone tissue in situ comprises: A) a two- component powder/liquid bone cement which upon mixing forms a self~hardening cement paste; and B) a third component consisting of a liquid which essentially is non-miscible with the cement paste and which is suitable to be washed out after hardening of said mixture in situ, resulting in a porous bone substituting material, whereby C) said injectable mixture comprises an X-ray contrast agent which is an organic substance.The injectable bone substitute material for bone augmentation has adaptable mechanical properties, an optimal radio-opacity without any inorganic X-ray contrast agent and therefore good biocompatibility.

La présente invention concerne un mélange injectable destiné à remplacer des tissus osseux in situ, comprenant: (A) un ciment osseux à deux composantes poudre/liquide qui, lorsqu'elles sont mélangées, forment une pâte de type ciment auto-durcissante; et (B) une troisième composante comprenant un liquide qui est sensiblement non miscible avec la pâte de type ciment et qui peut être extraite par lavage après durcissement dudit mélange in situ, pour donner une matière de substitution d'os poreuse. Selon l'invention, C) le dit mélange injectable comprend un agent de contraste aux rayons X qui est une substance organique. La matière de substitution d'os injectable permettant l'augmentation de la masse osseuse, a des propriétés mécaniques réglables, une opacité radio optimale sans emploi d'un quelconque agent de contraste aux rayons X minéral, et ainsi une bonne biocompatibilité.

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