Improved process for reductive hydrolysis of nitriles

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 31/20 (2006.01) C07C 29/00 (2006.01) C07C 31/02 (2006.01) C07C 31/38 (2006.01) C07C 253/30 (2006.01) C07C 255/12 (2006.01) C07D 213/30 (2006.01) C07D 307/33 (2006.01) C07D 307/42 (2006.01)

Patent

CA 2209656

This invention concerns processes for the reductive hydrolysis of nitriles to alcohols utilizing as a catalyst a transition metal complex of the formula MHZ(CO)Ln(PR3)2 wherein: M is a transition metal selected from the group consisting of: Fe, Ru and Os; Z is an anionic ligand; L is a neutral ligand; n is 0 or 1; and PR3 is a phosphine ligand.

La présente invention concerne des procédés d'hydrolyse de nitriles par réduction, donnant des alcools, avec comme catalyseur un complexe métallique de transition ayant pour formule MHZ(CO)L¿n?(PR¿3?)¿2?, M étant un métal de transition choisi dans le groupe constitué par le fer, le ruthénium et l'osmium, Z étant un coordinat anionique, L étant un coordinat neutre, n étant égal à 0 ou 1, et PR¿3? étant un coordinat de phosphine.

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