Liposome preparation by single-pass process

Details Liposome preparation by single-pass process Liposome preparation by single-pass process

A - Human Necessities

61

K

A61K 9/127 (2006.01) B01D 1/18 (2006.01)

Patent

CA 2668743

The present invention relates to a method of preparing liposomes in a singlepass mode. The method comprises the extusion of a solution or suspension through a porous device and subsequently passing said suspension or solution through a nozzle. Passing the suspension through said nozzle may result in an atomisation of the suspension or solution into droplets which might be employed in a subsequent spray-drying or spray-freezing process.

La présente invention concerne un procédé de préparation de liposomes dans un mode à simple passage. Le procédé comprend l'extrusion d'une solution ou d'une suspension à travers un dispositif poreux et, par la suite, le passage de ladite suspension ou solution à travers une buse. Le passage de la suspension à travers ladite buse peut conduire à une atomisation de la suspension ou solution en gouttelettes qui peuvent être employées dans un procédé ultérieur de séchage par pulvérisation ou de congélation par pulvérisation.

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