C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 38/16 (2006.01) C07K 14/29 (2006.01) C07K 16/12 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2331845
Compounds and methods for the diagnosis and treatment of Ehrlichia infection, in particular human granulocytic ehrlichiosis, are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of an Ehrlichia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Ehrlichia infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
Composés et procédés servant à diagnostiquer et à traiter l'infection par Ehrlichia, en particulier l'ehrlichiose granulocytique humaine. Ces composés comprennent des polypeptides contenant au moins une partie antigénique d'un antigène d'Ehrlichia et des séquences d'ADN codant ces polypeptides. Compositions pharmaceutiques et vaccins comprenant ces polypeptides ou ces séquences d'ADN. On peut utiliser des trousses de diagnostic contenant ces polypeptides ou ces séquences d'ADN, ainsi qu'un réactif de détection approprié afin de détecter l'infection par Ehrlichia chez des patients et dans des spécimens biologiques. L'invention concerne également des anticorps dirigés contre ces polypeptides.
Houghton Raymond L.
Lodes Michael J.
Mcneill Patricia D.
Reed Steven G.
Corixa Corporation
Gowling Lafleur Henderson Llp
LandOfFree
Compounds and methods for the diagnosis and treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds and methods for the diagnosis and treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and methods for the diagnosis and treatment of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1993948