Fluoroalkyl/alkenyl-substituted benzoylguanidines, process...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/22 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 311/47 (2006.01) C07C 317/32 (2006.01) C07C 317/44 (2006.01) C07C 323/44 (2006.01) C07D 207/337 (2006.01) C07D 213/58 (2006.01) C07D 215/14 (2006.01) C07D 217/16 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2157856

There are described benzoylguanidines of the formula I (See formula I) having the definitions of R(l) to R(4) indicated in the text, and their pharmaceutically tolerable salts. They are obtained by reaction of a compound II (See formula II) with guanidine. They are outstanding agents for the treatment of disorders of the cardiovascular system.

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