Multiheteroaryl compounds as inhibitors of h-pgds and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/14 (2006.01) A61K 31/167 (2006.01) A61K 31/425 (2006.01) A61P 11/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2736955

Multiheteroaryl compounds, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical use in the prevention and treatment of prostaglandin D2 mediated diseases and conditions that may be modulated by the inhibition of hematopoietic prostaglandin D synthase (H- PGDS).

L'invention concerne des composés multihétéroaryles, leur préparation, des compositions pharmaceutiques les contenant, ainsi que leur utilisation pharmaceutique dans la prévention et le traitement des maladies et des affections induites par la prostaglandine D2 et pouvant être modulées par l'inhibition de la prostaglandine D synthase hématopoïétique (H-PGDS).

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