Recombinant conglutinin and producing method thereof

Details Recombinant conglutinin and producing method thereof Recombinant conglutinin and producing method thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2400143

The present invention is directed to a purified mannan-binding protein (MBP) having budding inhibition activity as determined by a method comprising steps of: (a) culturing cells in presence of virus(es) to prepare virus(es)-infected cells,(b) presenting the virus(es)-infected cells in presence or absence of the MBP, (c) comparing gross area of virus(es)- infected focus formed in the presence of the MBP with that formed in the absence of the MBP, and (d) evaluating from the comparison results in the step (c) an inhibition level by the MBP on budding of virus in said infected cells. The products of the present invention are used in the preparation of medicines and methods of detecting physiological activities.

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