Progesterone receptor modulators comprising pyrrole-oxindole...

A - Human Necessities – 61 – K

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A61K 31/404 (2006.01) A61P 5/24 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2573314

Pyrrole-oxindole derivatives useful as progesterone receptor antagonists, and methods for preparing the same, are provided. Pharmaceutical compositions containing these derivatives are described, as is the use thereof in contraception and hormone-related conditions.

La présente invention décrit des dérivés de pyrrole-oxindole utilisés comme antagonistes des récepteurs de la progestérone, ainsi que les méthodes permettant de synthétiser lesdits dérivés. La présente invention décrit également des préparations pharmaceutiques comprenant lesdits dérivés, ainsi que l'utilisation desdites préparations à des fins contraceptives ou pour traiter des affections d'origine hormonale.

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