Preparation of 1-(4-chlorobenzoyl)-5-...

C - Chemistry – Metallurgy – 07 – D

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260/207.1

C07D 209/26 (2006.01) C07D 207/28 (2006.01)

Patent

CA 1148540

Abstract of the Disclosure The invention relates to a process for the production of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetoxy- acetic acid (known to be useful as an antiphlogistic agent) which comprises reacting a-(4-chlorobenzoyl)-4-methoxy- phenylhydrazine hydrochloride or sulphonate with laevulinoyl- oxyecetic acid and cyclizing the resulting hydrazone to obtain a product free from 1-benzoyl-5-methoxy-2-methyl-3- indolylacetoxyacetic acid. TP 28

363045

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