Process for the preparation of cyclic diketones

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 49/623 (2006.01) C07C 45/45 (2006.01) C07C 45/54 (2006.01) C07C 45/57 (2006.01) C07C 45/60 (2006.01) C07C 49/733 (2006.01) C07C 315/04 (2006.01) C07C 319/20 (2006.01) C07C 323/22 (2006.01) C07D 213/50 (2006.01) C07D 307/79 (2006.01) C07C 317/44 (2006.01) C07C 323/62 (2006.01)

Patent

CA 2424803

The present invention relates to a process for the preparation of compounds of formula I (see formula I), wherein the substituents are as defined in claim 1, by conversion of a compound of formula II (see formula II) to a salt of formula III (see formula III), reaction of that compound with a compound of formula IV X-C(O)-Q (IV), wherein X is a leaving group, to form a compound of formula V (see formula V), and treatment of that compound in the presence of a base with catalytic amounts of cyanide ions.

La présente invention concerne un procédé permettant de préparer des composés de formule I (voir la formule I), où les substituants sont définis conformément à la revendication 1, par conversion d'un composé de formule II (voir la formule II) en un sel de formule III (voir la formule III), réaction de ce composé avec un composé de formula IV X-C(O)-Q (IV), où X est un groupe partant, pour former un composé de formule V (voir la formule V), et traitement de ce composé en présence de quantités catalytiques d'ions cyanure.

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