Inhibitors of catalytic antibodies

Details Inhibitors of catalytic antibodies Inhibitors of catalytic antibodies

C - Chemistry, Metallurgy

07

K

530/15.06, 530/3

C07K 14/47 (2006.01) A61K 35/16 (2006.01) A61K 38/02 (2006.01) C07K 1/36 (2006.01) C07K 14/575 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2037199

ABSTRACT Specific, selective inhibitors of catalytic antibodies both synthetic and naturally occurring, their use and compositions thereof are disclosed. In particular, an inhibitor preventing the hydrolysis of the peptide bond between amino acid residues 16 and 17 in the neurotransmitter vasoactive intestinal peptide (VIP) by an anti-VIP catalytic autoantibody is disclosed.

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