C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 43/00 (2006.01) C07J 63/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 2253346
The present invention relates to a compound having the formula A-B-C, wherein A is a hydroxyl containing steroidal hormone; C is a nitrite or nitrate containing compound; and B is lower alkyl, lower alkenyl, lower alkynyl, and to pharmaceutical compositions thereof. These compounds are anti-inflammatory and vasodilation agents.
La présente invention se rapporte à un composé représenté par la formule A-B-C, dans laquelle A est une hormone stéroïdique contenant un groupe hydroxyle, C est un composé contenant un nitrate ou nitrite et B est alkyle inférieur, alkényle inférieur, alkynyle inférieur. L'invention se rapporte également à des compositions pharmaceutiques de ces composés utiles en tant qu'agents anti-inflammatoires et vasodilatateurs.
Currie Mark G.
Tjoeng Foe S.
Zupec Mark E.
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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