Method for determining asthma susceptibility

Details Method for determining asthma susceptibility Method for determining asthma susceptibility

G - Physics

01

N

G01N 33/68 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2354673

A method for determining whether an individual is susceptible for asthma is disclosed. In addition, a method for predicting the severity of asthma in a patient is also disclosed. These methods involve determining whether an individual carries an allelic variation in the IL-4 receptor that leads to increased receptor signaling as a predictor of asthma and asthma severity.

La présente invention concerne une méthode permettant de déterminer si une personne est sensible à l'asthme. Cette invention concerne en outre une méthode permettant de prévoir la gravité de l'asthme chez un patient. Ces méthodes consistent à déterminer si une personne est porteuse d'une variation allèlique du récepteur IL-4, qui conduit à une signalisation augmentée du récepteur que l'on considère comme un prédicteur de l'asthme et de sa gravité.

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