Novel antibiotic alternatives

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/24 (2006.01) A61K 35/66 (2006.01) A61K 38/16 (2006.01) A61P 31/04 (2006.01) C12N 15/31 (2006.01) C12N 15/81 (2006.01)

Patent

CA 2559662

The present invention relates to two recombinant colicin expression systems, one utilizing a yeast expression system that produces a protein that is inexpensive to purify, and the other utilizing a plasmid expression system to be used as a probiotic culture. The recombinant colicins provide effective alternatives to conventional antibiotics and may be used to improve the efficiency of pork production, and the safety of its products.

La présente invention concerne de systèmes d'expression de colicine de recombinaison, l'un utilisant un système d'expression de levure qui produit une protéine qu'on peut purifier à faible coût et, l'autre utilisant un système expression de plasmide utilisé comme culture probiotique. Ces colicines de recombinaison offrent des alternatives efficaces aux antibiotiques conventionnels et peuvent être utilisées pour améliorer l'efficacité de la production de porc et l'innocuité de ses produits.

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