Botulinum toxin screening assays

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01)

Patent

CA 2558758

Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to FGFR3 to a governmental or regional regulatory authority.

La présente invention a trait à des procédés de détection d'activité de toxine botulinique de type A, des procédés de criblage de molécules capable d'être en compétition avec la liaison de récepteur de toxine botulinique de type A, des procédés de réduction de l'activité de toxine botulinique de type A chez un humain et des procédés de commercialisation d'une neurotoxine capable d'une liaison sélective au récepteur 3 du facteur de croissance des fibroblastes auprès d'une autorité gouvernementale ou régionale.

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