Method for fermentative production of n-acetyl-d-glucosamine...

C - Chemistry – Metallurgy – 12 – P

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C12P 19/26 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2615511

N-Acetyl-D-glucosamine can be produced by cultivating a mold capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum strain AB10282 (FERM BP-10623) or Trichoderma harzianum strain AB10283 (FERM BP-10624), in a culture medium supplemented with a carbon source other than chitin and chitin oligosaccharide and a nitrogen source to produce and accumulate N-acetyl-D- glucosamine in the culture medium and then collecting N-acetyl-D-glucosamine from the culture medium.

La N-acétyl-D-glucosamine peut être produite selon la présente invention en cultivant une moisissure capable de produire la N-acétyle-D-glucosamine, telle qu~une souche de Trichoderma hamatum AB10282 (FERM BP-10623) ou une souche de Trichoderma harzianum AB10283 (FERM BP-10624), dans un milieu de culture complété par une source de carbone autre que la chitine et un oligosaccharide de chitine et une source d'azote de façon à produire et accumuler la N-acétyl-D-glucosamine dans le milieu de culture et puis à recueillir la N-acétyl-D-glucosamine dans le milieu de culture.

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