Process for preparing a 16.beta.-methyl steroid and new...

C - Chemistry – Metallurgy – 07 – J

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C07J 71/00 (2006.01) C07J 1/00 (2006.01) C07J 7/00 (2006.01) C07J 13/00 (2006.01) C07J 21/00 (2006.01) C07J 33/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2150738

L'invention concerne la préparation d'un produit de formule (I): (See formula I) au départ de la cyanhydrine de formule (II): (See formula II) dans laquelle les cycles A et B représentent:où K est un radical oxo ou un groupe protecteur du radical oxo et R1 un reste éther ou ester, ainsi que des intermédiaires nouveaux. Le produit de formule (I) est un intermédiaire utilisable pour la synthèse de la bétamétasone, qui est un anti-inflammatoire de la famille des corticostéroïdes.

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