A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/21 (2006.01) A61K 8/24 (2006.01) A61K 8/55 (2006.01) A61K 8/64 (2006.01) A61Q 11/00 (2006.01)
Patent
CA 2469431
The present invention relates to oral care compositions, especially toothpastes, comprising: a safe and effective amount of phosphopeptide- amorphous calcium phosphate complex ("PP-ACP"); a safe and effective amount of a fluoride ion source; a pharmaceutically-acceptable topical, oral carrier, and a safe and effective amount of a calcium chelator, wherein the composition has improved fluoride stability. This invention further relates to a method of maintaining the fluoride levels in an oral care composition comprising a safe and effective amount of PP-ACP, a safe and effective amount of a fluoride ion source, and a pharmaceutically-acceptable topical, oral carrier, by adding, to the composition, a safe and effective amount of a calcium chelator.
L'invention concerne des compositions d'hygiène bucco-dentaire, en particulier des dentifrices, comprenant: une dose sûre et efficace de complexe de phosphate amorphe de calcium phosphopeptidique ("PP-ACP"); une dose sûre et efficace de source d'ion fluorure; un excipient oral, topique, pharmaceutiquement acceptable; et une dose sûre et efficace d'un chélateur calcique; ladite composition présentant une stabilité de fluorure améliorée. L'invention concerne en outre un procédé permettant de maintenir les niveaux de fluorure dans une composition d'hygiène bucco-dentaire comprenant: une dose sûre et efficace de PP-ACP; une dose sûre et efficace de source d'ion fluorure; et un excipient oral, topique, pharmaceutiquement acceptable, par ajout à la composition d'une dose sûre et efficace d'un chélateur calcique.
Dixon Cloyd Jr.
Kaminski Michael Anthony
Ledgley Law
The Procter & Gamble Company
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