Method and composition for the treatment of parkinson's disease

A - Human Necessities – 61 – K

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A61K 31/425 (2006.01) A61K 31/34 (2006.01)

Patent

CA 2145521

Neuropsychiatric symptoms of Parkinson's Disease and particularly the symptoms of apathy-amotivation and mental slowing can be ameliorated by treating a patient suffering from Parkinson's Disease with a histamine H2-antagonist that passes the blood brain barrier. Suitable H2-antagonists include famotidine and ranitidine. The H2-antagonists may be co-adminis- tered with other compounds such as histamine H1-antagonists which are known to be useful in the treatment of Parkinson's Disease, and can be formulated with such other compounds into a therapeutic composition.

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