Heteroannulation process

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 221/06 (2006.01) C07C 231/12 (2006.01) C07D 215/22 (2006.01) C07D 215/227 (2006.01) C07D 215/48 (2006.01) C07D 221/10 (2006.01) C07D 221/16 (2006.01) C07D 457/00 (2006.01) C07D 471/06 (2006.01) C07D 491/052 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2092782

X-8328 ABSTRACT A heteroannulation process for preparing piperidones and tetrahydropyridones by reacting an appropriately substituted enamine with an acryloyl derivative wherein a leaving group occupies the carbonyl; a process for cleaving a l-phenylethyl group from an acylated amino group or an heterocyclic nitrogen atom adjacent to a carbonyl group, particularly that on the nitrogen atom of the products of the heteroannulation process, is also provided.

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