C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) C12N 15/00 (2006.01) C12Q 1/70 (2006.01) C07K 14/18 (2006.01) C12N 15/51 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2735882
The present invention provides for novel methods of producing high levels of infectious HCV genotype 1 virus particles in cell culture systems. The availability of HCV genotype 1 virus (principally associated with liver disease in most regions of the world) that can undergo the complete viral cycle in cultured cells is beneficial for the discovery and development of novel therapies for the treatment of HCV.
La présente invention concerne de nouveaux procédés de production de taux élevés de particules de virus VHC de génotype 1 infectieuses dans des systèmes de culture de cellules. La disponibilité du virus VHC de génotype 1 (principalement associé à une maladie hépatique dans la plupart des régions du monde) qui peut subir le cycle viral complet dans des cellules en culture est bénéfique pour la découverte et le développement de nouvelles thérapies pour le traitement du VHC.
Mccown Matthew
Najera Isabel
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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