A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/366 (2006.01) A61K 31/122 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2512666
A combination anticoagulation medicament including vitamin K with warfarin in an oral form is described. Between 50 and 5000 milligrams of vitamin K are combined in a single oral medication with 0.5 to 15 milligrams of warfarin for administration. The combination of vitamin K with warfarin in a single orally dosed form is a novel approach to improving the effectiveness of anticoagulation. The combination allows for broader application of warfarin in medical anticoagulation and reduces the variability of anticoagulation due to the influences of diet, additional medications, nutritional status, changes in physical condition, and potentially other factors. Use of the combination therapy improves the safety of warfarin as an appropriate anticoagulant for many medical conditions.
L'invention concerne un médicament combiné anticoagulant contenant de la vitamine K et de la warfarine dans une forme orale. Entre 50 et 5000 mg de vitamine K sont combinés à 0,5 à 15 mg de warfarine dans un monomédicament oral destiné à être administré. La combinaison de vitamine K à la warfarine dans une forme orale individuelle est une nouvelle manière d'améliorer l'anticoagulation. Ladite combinaison permet d'élargir le spectre d'application de la warfarine dans l'anticoagulation médicale et de réduire les variations de l'effet anticoagulation dues à des régimes, à d'autres médicaments, à l'état nutritionnel, à des variations de la condition physique, et à d'autres facteurs potentiels. L'utilisation de la thérapie combinée selon l'invention permet d'augmenter l'innocuité de la warfarine en tant qu'agent anticoagulant approprié dans le cas d'un grand nombre de troubles médicaux.
Finlayson & Singlehurst
Flacco-Nesselroad Family Trust
Nesselroad James M. III
LandOfFree
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