Remineralizing products and methods for teeth

Details Remineralizing products and methods for teeth Remineralizing products and methods for teeth

A - Human Necessities

61

K

A61K 33/00 (2006.01) A61K 8/19 (2006.01) A61K 8/24 (2006.01) A61K 9/68 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2224274

Products and methods are provided for the remineralization of lesions formed in the subsurfaces of teeth and/or mineralization of tubules in exposed dentin of teeth, wherein the products generally contain at least one water-soluble calcium salt, at least one divalent metal salt other than calcium salt, at least one water-soluble phosphate salt, and, optionally, at least one water- soluble fluoride salt. The water-soluble salts are then mixed to form an aqueous mixed solution having a pH of from about 4.5 to about 7Ø Cations released by the divalent metal salt stabilize the aqueous solution such that phosphate and calcium ions released by the salts do not react to any large extent until the product is introduced into the oral cavity and, upon introduction into the oral cavity, the ions do not rapidly precipitate. This gives the cations and anions sufficient time to diffuse through the tooth surface to the lesion(s) and/or tubules where the ions form a precipitate, thereby remineralizing the lesion(s) and/or mineralizing the tubule(s).

L'invention concerne des produits et des procédés permettant une reminéralisation des lésions formées sous la surface des dents et/ou la minéralisation des tubules de la dentine, lorsque celle-ci est mise à nu. Ces produits contiennent au moins un sel de calcium hydrosoluble, au moins un sel d'un métal divalent autre que le calcium, au moins un sel phosphate hydrosoluble et, éventuellement, au moins un sel fluorure hydrosoluble. Les sels hydrosolubles sont ensuite mélangés pour former une solution aqueuse mixte ayant un pH entre 4,5 environ et 7,0 environ. Les cations libérés par le sel de métal divalent stabilisent la solution aqueuse, si bien que les ions phosphate et les ions calcium libérés par les sels ne réagissent pas d'une manière significative avant l'introduction dans la cavité buccale. Après l'introduction dans la cavité bucale, les ions ne précipitent pas rapidement. Ceci donne aux cations et aux anions assez de temps pour diffuser à travers la surface des dents et arriver aux lésions et/ou aux tubules, où les ions forment un précipité assurant la reminéralisation des lésions et/ou des tubules.

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