Fluorophenyl-substituted alkenylcarboxylic acid guanidides,...

Details Fluorophenyl-substituted alkenylcarboxylic acid guanidides,... Fluorophenyl-substituted alkenylcarboxylic acid guanidides,...

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/165 (2006.01) A61P 9/06 (2006.01) A61P 9/10 (2006.01) C07C 277/08 (2006.01)

Patent

CA 2177007

Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them compounds of the formula I: Image wherein the substituents R(1) to R(7) are as defined in the claims, and the pharmaceutically tolerated salts thereof are valuable inhibitors of the cellular sodium/ proton exchanger (Na+/H+ exchanger) . They are therefore outstandingly suitable for the treatment of all diseases attributable to increased Na+/H+ exchange.

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