Method for correcting a lipid imbalance in a subject

Details Method for correcting a lipid imbalance in a subject Method for correcting a lipid imbalance in a subject

A - Human Necessities

61

K

A61K 31/167 (2006.01) A61P 3/00 (2006.01) A61P 19/08 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2667091

The present invention relates to methods for the treatment of a disease or condition associated with lipid imbalance, comprising (a) decreasing arachidonic acid (AA) levels, (b) increasing docosahexaenoic acid (DHA) levels, (c) increasing DHA/AA ratio or (d) any combination of (a)-(c) in a subject using fenretinide. The invention also relates to diagnostic and screening methods based on the determination of lipid levels.

La présente invention concerne des procédés de traitement d'une maladie ou condition associée à un déséquilibre lipidique, comprenant (a) la diminution des taux d'acide arachidonique (AA), (b) l'augmentation des taux d'acide docosahexaénoïque (DHA), (c) l'augmentation du rapport DHA/AA ou (d) toute combinaison de (a) à (c) chez un sujet en utilisant le fenrétinide. L'invention concerne également des procédés de diagnostic et de criblage basés sur la détermination de taux de lipides.

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