C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2293270
A mammalian protein, prenylcysteine carboxyl methyltransferase, involved in further post-translational modification of prenylated proteins, is cloned, characterized, and expressed in non-native cells. Such membrane preparations can be used to screen for inhibitors of prenylcysteine carboxyl methyltransferase activity.
L'invention concerne une protéine de mammifère, la prénylcystéine carboxyle méthyltransférase, impliquée dans la modification post-traductionnelle de protéines prénylées, qui est clonée, caractérisée et exprimée dans des cellules non natives. Les préparations membranaires en question peuvent être utilisées pour rechercher par criblage des inhibiteurs de l'activité de prénylcystéine carboxyle méthyltransférase.
Gowling Lafleur Henderson Llp
New York University
LandOfFree
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