A rapid non-invasive method for the diagnosis of a...

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G01N 33/88 (2006.01)

Patent

CA 2414897

The invention relates to a non-invasive method for the diagnosis of cardiovascular disease in a subject, comprising the steps of measuring in a urine sample the concentrations of one or more thromboxanes, the conductivity, and the concentration of at least one additional marker of cardiovascular disease, which marker can be chosen from apolipoprotein (a), conjugated dienes and lipid peroxides. Diagnosing the presence of cardiovascular disease in said subject is carried out by comparison of the analytical results with pre- determined reference values. The invention further relates to a kit for the rapid diagnosis of cardiovascular diseases.

L'invention concerne un procédé non vulnérant de diagnostic de maladie cardio-vasculaire chez un patient, ce procédé comprenant les étapes suivantes consistant à mesurer dans un échantillon d'urine les concentrations d'une ou plusieurs thromboxanes, la conductivité et la concentration d'au moins un marqueur supplémentaire de maladie cardio-vasculaire, lequel peut être choisi dans le groupe constitué par une apolipoprotéine (a), des diènes conjugués et des peroxydes lipidiques. Le diagnostic de la présence d'une maladie cardio-vasculaire chez ce patient s'effectue par comparaison des résultats de l'analyse avec des valeurs de référence déterminées. L'invention concerne en outre un nécessaire permettant d'établir un diagnostic rapide de maladies cardio-vasculaires.

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