Op-3-induced morphogenesis

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/18 (2006.01) A61K 6/00 (2006.01) A61K 35/12 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) C07K 14/475 (2006.01) C07K 14/51 (2006.01) C07K 16/22 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) A61F 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2147598

Disclosed are (1) nucleic acid and amino acid sequences for a novel morphogenic protein; (2) methods for producing and expressing the protein in a biologically active form; and (3) methods for utilizing the protein to induce tissue morphogenesis in a mammal, including methods for increasing a progenitor cell population in a mammal, methods for stimulating progenitor cells to differentiate and maintain their differentiated phenotype in vivo or in vitro, methods for inducing tissue-specific growth in vivo and methods for the replacement of diseased or damaged tissue in vivo.

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