N-alkylcarbonyl-amino acid ester and n-alkylcarbonyl-amino...

C - Chemistry – Metallurgy – 07 – C

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C07C 233/63 (2006.01) A61K 31/223 (2006.01) A61K 31/365 (2006.01) A61P 11/14 (2006.01) A61P 17/00 (2006.01) A61P 25/34 (2006.01) C07D 307/32 (2006.01)

Patent

CA 2602075

The present invention generally relates to refreshing, soothing, and cooling compounds that affect sensory processes. More particularly, the present invention pertains to certain N-alkylcarbonyl-amino acid ester and N- alkylcarbonyl-amino lactone compounds as described herein; compositions and articles comprising such compounds; and methods of treatment, for example, methods of alleviating the discomforts of irritation, itch, and pain in the skin and in the linings of the oral cavity and upper respiratory tract, for example, in methods of treatment of cough and/or asthma.

La présente invention concerne d'une manière générale le rafraîchissement, l'apaisement et le refroidissement de composés qui affectent des processus sensoriels. Cette invention concerne en particulier certains ester d'acideN-alkylcarbonyl-amino et composés lactone N-alkylcarbonyl-amino décrits dans les spécifications, des compositions et des articles comprenant ces composés et des techniques de traitement, par exemple, des techniques permettant d'atténuer l'inconfort d'une irritation, d'une démangeaison et d'une douleur cutanée et du recouvrement de la cavité orale et de la voie respiratoire supérieure, par exemple, dans des techniques de traitement de la toux et/ou de l'asthme.

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