Process for the production of the piperidine derivative...

Details Process for the production of the piperidine derivative... Process for the production of the piperidine derivative...

C - Chemistry, Metallurgy

07

D

C07D 211/22 (2006.01) C07C 69/738 (2006.01)

Patent

CA 2450313

The present invention relates to processes for preparing certain piperidine derivatives, including fexofenadine (F) (see Scheme), the active ingredient in the non-sedating antihistamine sold in the U.S. under the designation "Allegra®". This invention also relates to novel synthetic intermediates useful in the processes of the present invention.

La présente invention concerne des procédés permettant la préparation de certains dérivés de pipéridine, y compris la fexofénadine (voir schéma), l'ingrédient actif dans l'antihistamine vendu aux Etats Unis sous la désignation <= Allegra >=®. L'invention concerne également de nouveaux intermédiaires de synthèse utilisés dans les procédés de l'invention.

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