Polysaccharide-derived nitric oxide-releasing carbon-bound...

Details Polysaccharide-derived nitric oxide-releasing carbon-bound... Polysaccharide-derived nitric oxide-releasing carbon-bound...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2628055

The invention relates to compounds capable of releasing nitric oxide wherein the compounds comprise a saccharide and at least one nitric oxide-releasing diazeniumdiolate [N2O2] functional group, which is bonded directly to a carbon atom of the saccharide, and methods for preparing the same. The invention further comprises the treatment of biological disorders treatable by the administration of nitric oxide.

L~invention concerne des composés capables de libérer de l~oxyde nitrique, lesdits composés comprenant un saccharide et au moins un groupe fonctionnel diazéniumdiolate [N2O2] libérant de l~oxyde nitrique, ledit groupe étant directement lié à un atome de carbone du saccharide, ainsi que des procédés de préparation de ces composés. L~invention concerne également le traitement de troubles biologiques par l~administration d~oxyde nitrique.

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