Method of producing infectious reovirus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 39/15 (2006.01) C07K 14/14 (2006.01) C12N 7/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2415749

A simple and efficient method of producing mammalian reovirus is developed using HEK 293 cells. The method provides for fast production of reovirus in high yield. Furthermore, this method provides for a simpler purification procedure of the produced reovirus.

On a mis au point un procédé simple et efficace de production de réovirus de mammifère dans lequel on utilise des cellules HEK 293. Le procédé permet de produire rapidement des réovirus avec un rendement élevé. Ce procédé comprend également une procédure de purification simplifiée des réovirus produits.

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