Calcium channel compositions and methods

Details Calcium channel compositions and methods Calcium channel compositions and methods

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2074719

The subject invention provides an isolated DNA fragment, comprising a sequence of nucleotides encoding the .gamma.-subunit of a mammalian calcium channel, wherein the sequence of nucleotides is selected from sequences of nucleotides encoding a protein having the sequence of amino acids set forth in Figure 1, sequences of nucleotides that encode a .gamma.-subunit of a mammalian calcium channel and hybridize under non-stringent conditions to DNA encoding the protein set forth in Figure 1, or sequences of nucleotides that encode a .gamma.-subunit of a mammalian calcium channel and hybridize under non-stringent conditions to DNA having the sequence set forth in Figure 1. The invention provides a useful tool in studying the function of Ca+2 channels in mammalian cells.

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