In vitro repair of bone and/or cartilage defects

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/54 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 27/38 (2006.01) A61L 27/58 (2006.01) A61F 2/30 (2006.01) A61K 35/12 (2006.01) A61K 38/18 (2006.01) A61K 38/39 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2378079

The present invention relates to methods and materials for in vivo repair of cartilage (70) or bone (23) and cartilage defects in mammals. The invention relates to membranes (21, 50) carrying a composition comprising at least one stimulation molecule, which is capable of inducing signal transduction in chondroblasts/chondrocytes and/or osteoblasts/osteocytes. Furthermore the invention relates to a method for the preparation of chondroblasts/chondrocytes (80) and/or osteoblasts/osteocytes suspensions (24).

La présente invention concerne des méthodes et des matériaux permettant d'effectuer une réparation in vivo du cartilage ou de défauts osseux et du cartilage chez des mammifères. L'invention concerne également des membranes porteuses d'une composition qui renferme au moins une molécule de stimulation capable d'induire une transduction de signal dans les chondroblastes/chondrocytes et/ou les ostéoblastes/ostéocytes. Cette invention concerne enfin une méthode de préparation de suspensions à base de chondroblastes/chondrocytes et/ou d'ostéoblastes/ostéocytes.

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