Omega-hydrofluoroalkyl ethers, precursor carboxylic acids...

C - Chemistry – Metallurgy – 07 – C

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C07C 43/12 (2006.01) A61K 9/00 (2006.01) A61K 49/04 (2006.01) A61K 49/18 (2006.01) A61K 49/22 (2006.01) A62D 1/00 (2006.01) A62D 1/02 (2006.01) B01D 12/00 (2006.01) B23K 35/38 (2006.01) C07C 41/24 (2006.01) C07C 43/192 (2006.01) C07C 43/313 (2006.01) C07C 49/175 (2006.01) C07C 59/135 (2006.01) C07C 69/708 (2006.01) C07C 217/26 (2006.01) C07C 235/06 (2006.01) C07C 255/13 (2006.01) C07C 265/04 (2006.01) C07D 319/06 (2006.01) C07F 7/08 (2006.01) C08J 9/14 (2006.01) A62D 3/00 (2006.01)

Patent

CA 2190116

Normally liquid, omega-hydrofluoroalkyl ether compounds (and selected mixtures thereof) have a saturated perfluoroaliphatic chain of carbon atoms interrupted by one or more ether oxygen atoms. The compounds can be prepared, e.g., by decarboxylation of the corresponding fluoroalkyl ether carboxylic acids and are useful, e.g., in cleaning and drying applications.

La présente invention concerne un procédé de prévision de la conformation et de la fonctionnalité d'une molécule. Une première opération du procédé consiste à exécuter plusieurs recuits simulés afin de révéler les régions peuplées et non peuplées d'un espace de conformation multidimensionnel. La seconde opération consiste à effectuer une simulation à température fixe en n'échantillonnant qu'à partir des régions peuplées révélées au cours de la première opération.

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