Methods of administering an ampa receptor antagonist to...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A61K 31/15 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2246560

The invention relates to a method of treating dyskinesias associated with dopamine agonist therapy in a mammal which comprises administering to said mammal an effective amount of an antagonist of the AMPA receptor. Dopamine agonist therapy, as referred to in the present invention, is generally used in the treatment of a central nervous system disorder such as Parkinson's disease.

L'invention porte sur une méthode pour traiter les dyskinésies associées à la thérapie par un agoniste de la dopamine chez un mammifère, consistant à administrer audit mammifère une quantité efficace d'un antagoniste du récepteur AMPA. La thérapie, à l'aide d'un agoniste de la dopamine, comme on le spécifie dans la présente invention, est généralement employée pour le traitement des troubles du système nerveux central, comme la maladie de Parkinson.

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