Fasudil-containing preparation and method of improving...

A - Human Necessities – 61 – K

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A61K 31/551 (2006.01) A61K 9/08 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2559630

Fasudil-containing preparations that despite the use of a container excelling in the visibility of contents without particularly blocking of light, exhibit high stability against light; and a method of improving the stability of the preparations against light, or storing the same. By regulating the pH value of aqueous solution of fasudil charged in a colorless transparent container to <=5.5, there can be provided fasudil-containing preparations excelling in stability against light; and can be provided a method of improving the stability of the aqueous solution of fasudil against light, or storing the same.

Il est prévu des préparations contenant du fasudil qui malgré l~utilisation d~un conteneur excellent en termes de visibilité du contenu sans blocage particulier de la lumière, présentant une stabilité élevée contre la lumière, et un procédé pour améliorer la stabilité des préparations contre la lumière, ou stockage desdites préparations. En régulant l~acidité pH à <= 5,5 de la solution aqueuse de fasudil versée dans un conteneur transparent incolore, on peut obtenir des préparations contenant du fasudil d~une stabilité excellente contre la lumière ; un procédé pour améliorer la stabilité de la solution aqueuse de fasudil contre la lumière, ou stockage de ladite solution.

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